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EU new drug approval studies "have too few patients to evaluate safety"

For medicines intended for chronic use, the number of patients studied before regulatory approval in the European Union (EU) is insufficient to properly evaluate safety and long-term efficacy, and this points to a need for new EU legislation, say researchers writing in this week's PLOS Medicine.

Published
1 hour ago
From
Pharma Times
People doing well on HIV therapy "should be eligible" for life insurance cover

The long-term effectiveness of antiretroviral therapy means that many HIV-positive people should be eligible for affordable life insurance, European investigators write in the online edition of AIDS. Even

Published
3 hours ago
By
Michael Carter
Self-testing and home treatment initiation triples uptake of HIV treatment in Malawi

Offering people the opportunity to self-test at home and then start antiretroviral therapy after counselling at home, together with home delivery of antiretroviral drugs, increased the number

Published
21 March 2013
By
Keith Alcorn
Swiss police arrest "healer" accused of infecting 16 with HIV

Swiss police have arrested a self-styled healer after he stopped attending a trial where he stands accused of infecting 16 people with HIV using acupuncture needles.

Published
18 March 2013
From
Reuters
French researchers report 14 patients in 'remission' after controlling HIV for over 4 years off treatment

Two weeks ago, the announcement that a baby had been ‘functionally cured’ of HIV disease with the use of very early antiretroviral therapy (ART) caused great excitement at the

Published
16 March 2013
By
Gus Cairns
Post-Treatment HIV-1 Controllers with a Long-Term Virological Remission after the Interruption of Early Initiated Antiretroviral Therapy ANRS VISCONTI Study

Our results show that early and prolonged cART may allow some individuals with a rather unfavorable background to achieve long-term infection control and may have important implications in the search for a functional HIV cure.

Published
15 March 2013
From
PLoS Pathogens
Over 2,000 People Have Stopped HIV Meds for Prayer in Ghana

A total of 2,248 people with HIV/AIDS on antiretroviral treatment in Ghana have stopped taking their medications to seek help at prayer camps and from traditional healers.

Published
15 March 2013
From
Poz magazine news
More HIV 'cured': first a baby, now 14 adults

Two weeks after the revelation that a baby has been "cured" of HIV, reports suggest that a similar treatment can cure some adults too. Early treatment seems crucial, but does not guarantee success.

Published
15 March 2013
From
New Scientist
AIDS treatment Visconti’s coup

If the common factor between so-called post-treatment controllers can be identified, it will allow doctors to offer treatment withdrawal to those likely to benefit from it. It will also show researchers a chink in AIDS’s armour. If they can find something which they can insert into that chink to clear the disease in other people, too, the Visconti trial may come to be seen as a turning point in the war on AIDS.

Published
15 March 2013
From
The Economist
Computer models predict how patients will respond to HIV drugs

Results of a new study demonstrate that computer models can predict how HIV patients whose drug therapy is failing will respond to a new treatment. Crucially for patients in poorer countries, the models do not require the results of expensive drug resistance tests to make their predictions. The study also showed that the models were able to identify alternative drug combinations that were predicted to work in cases where the treatment used in the clinic had failed, suggesting that their use could avoid treatment failure.

Published
14 March 2013
From
Eurekalert Inf Dis
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